Thrax is a tall, extremely virulent, and unusually powerful pathogenic agent who appears in Osmosis Jones and serves as the film's main antagonist. He claims loudly: “Ebola is a case of dandruff compared to me!” and has killed numerous people before arriving in Frank. He carries a chain consisting of numerous chromosomes removed from other victims' hypothalamus as a trophy. His primary motivation for his infections is to go down in medical history as the world's deadliest virus and with each new body goes on to break his previous records. His left index finger is a long claw, which can melt the cellular equivalent of steel, consume cells and other viruses in flames, and alter the properties of other cells. His claw can even melt synthetic polyester fiber (though at a much slower rate), a feature that comes into play at the climax. His name is a play on the word anthraxalthough he does not cause the disease. It's never specified what kind of disease he causes, but he is mostly likely to be a fictional pathogenic agent. Red Death is sometimes a nickname for Smallpox. Thrax is killed at the film's climax when he falls into a tub of rubbing alcohol fighting with Osmosis on a pair of Shane DeTorre's artificial eyelashes.

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